Retinol on Human Skin Aging in East Asian Descent

Exclusion Criteria

• •skin condition in the areas of skin biopsy that would obscure results of analysis
• •topical creams or treatment to arms 2 weeks prior to study baseline visit
• •individuals with known hypersensitivity to retinoid class of agents (older group only)
• •prior anti-aging treatments to arms including retinol, microdermabrasion within 2 weeks of baseline visit
• •prior laser therapy or surgical procedure to arms
• •prior radiation or other trauma (extensive burns or abrasions) to arm skin
• •hormone-based therapy within 4 weeks of enrollment