Previous treatment with benzodiazepine or acetazolamide for Electrical Status Epilepticus in Sleep (ESES)

Current treatment with carbamazepine, phenytoin, oxcarbazepine, phenobarbital, vigabatrin or lamotrigine

Antiepileptic medication changes over the month prior to enrollment

Epileptic encephalopathy other than CSWS/LKS

Prior serious adverse reaction to benzodiazepines or acetazolamide

Sulfa allergy

Progressive underlying neurologic condition

Frequent seizures that would prevent the patient from maintaining a stable dose of medications

Female patient that has begun menses or is pregnant

Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome