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Effect of a Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help to Improve Exercise Capacity and Quality of Life in Breast Cancer
Integrative approaches to promote wellness and reduce the distress associated with cancer are considered as essential components of cancer care. In case, exercise training has been shown to produce many positive physiological and psychological benefits. Mindfulness-based stress reduction program shows similar beneficial effects, and especially in emotional distress management. The aim of the study is to examine the cumulative effect of an 8 week-exercise-training program combined with an MBSR program on cardio-respiratory fitness and quality of life in women with breast cancer. These effects are thought to be mediated in part through changes in underlying brain processes, that investigators will be put in light. Through telomerase activity, oxidative stress, mitochondrial respiration and blood cytokine level measurements, investigators could expect to better understand the effect of these combined training in breast cancer.
Age
18 - 65 years
Sex
FEMALE
Healthy Volunteers
No
Physiologie et EFR/ EA 3072 mitochondrie, stress oxydant et protection musculaire
Strasbourg, France
Start Date
May 12, 2015
Primary Completion Date
May 12, 2015
Completion Date
March 30, 2021
Last Updated
December 19, 2025
100
ACTUAL participants
Endurance exercise training
OTHER
Mindfulness-based-stress-reduction
OTHER
Both interventions together
OTHER
Vo2max measurements
OTHER
Telomerase activity on a blood sample
GENETIC
Quality of life (questionnaires)
OTHER
Cerebral IRMf
OTHER
Lead Sponsor
University Hospital, Strasbourg, France
NCT05245812
NCT05372640
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