Lead Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborators

Age

12 - 17 years

Sex

ALL

Healthy Volunteers

No

•The patient:
•and/or their parent(s)/guardian must be able to understand and provide informed consent in English or Spanish;
•is prescribed tacrolimus (either brand or generic formulation); and
•has been seen in the enrolling center's clinic at least twice in the last two years.

•The patient:
•received a transplant less than 18 months prior to enrollment;
•has had more than one transplant (including marrow replacement);
•or their parent(s)/guardian is actively psychotic or severely disoriented due to any cause, including hepatic encephalopathy (temporary exclusion);
•or their parent(s)/guardian has been diagnosed with severe intellectual disability as defined in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5);
•is not medically stable or is hospitalized;
•is currently enrolled in a study that aims to improve adherence to medical recommendations;
•is receiving cognitive behavioral therapy for confirmed or suspected diagnosis of Post-Traumatic Stress Disorder (PTSD) at enrollment;
•is receiving psychotropic medications for a confirmed or suspected diagnosis of PTSD.