Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
CHDI Foundation, Inc.
With
Dr. Glenn T. Stebbins (Rush University Medical Center )
The University of Texas Health Science Center, Houston
Nancy LaPelle
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Main criteria for inclusion:
1. HDGEC participant must be a participant in Enroll-HD (NCT No.: NCT01574053)
2. At least 18 years of age
3. Must be fluent in English and had his primary education in English
4. Must be willing and able to provide written informed consent
Pre-Manifest HDGECs
Criteria 1-4, and:
1. CAG length greater than or equal to 40
2. Disease Burden Score greater than or equal to 250 (calculated by the equation:
\[CAGn-35.5\] X age)
3. UHDRS Diagnostic Confidence Level (DCL) \< 3
4. At least five Pre-Manifest HDGEC participants should have a companion who is willing to participate in this study and complete the scale independently.
Early-Manifest (Stage 1\&2) HDGECs
Criteria 1-4, and:
1. CAG length greater than or equal to 36
2. DCL=4
3. UHDRS Total Functional Capacity (TFC) ≥7
4. Participants whose companion is willing to participate in this study and complete the scale independently
Main criteria for exclusion:
1. Significant cognitive or any other impairment sufficient to interfere with study associated tasks as judged by the study Investigator or the Investigator's designee
2. Currently participating in a clinical trial involving an investigational medicinal product
