Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Admitted to the Intensive Care Unit
Receiving invasive mechanical ventilation via endotracheal or tracheostomy tube
Presence of ARDS by Berlin Criteria (acute onset bilateral pulmonary infiltrates incompletely explained by left heart failure together with a PaO2/FiO2 of \<300 or SpO2/FiO2 \<315)
You may not be if
Inability to obtain surrogate consent
Presence of specified comorbidities:
1. pregnancy
2. pre-existing severe chronic obstructive pulmonary disease, defined as FEV1 documented \< 1L or baseline hypercapnia
3. cerebral edema
4. known intra-cranial abnormality
5. acute coronary syndrome
Endotracheal or tracheostomy cuff leak
Chest tube with persistent air leak
Severe hemodynamic instability (defined as attending judgment that the patient is unable to safely tolerate ventilator manipulations)
Presence of spontaneous respiratory activity as evidenced by examination of the ventilator waveform tracing
Intrinsic PEEP of \> 5 cmH2O
Assessment of study staff or patient's attending physician that the patient would not be a good study participant
Clareo Health | Stress Index to Individualize Mechanical Ventilation in ARDS
