Other endpoints:
* to determine whether high protein ONS influence on the nutritional status
* to determine whether high protein ONS influence on the quality of life
* to determine whether high protein ONS influence on the performance status
* to determine high protein ONS tolerability / ONS intake compliance
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
histological confirmed diagnosis of CRC in clinical stage IV
successful qualification to chemotherapy
performance status at least 80% according to Karnofsky scale and \<2 according to WHO/ECOG scale
cancer-related asymptomatic precachexia diagnosed
absence of contraindications to oral nutrition and practicable realization of oral nutrition
absence of severe, decompensated concomitant diseases
signed informed consent for the participation in the study
You may not be if
diagnosis of a malignant neoplasm in clinical stage I-III
disqualification from oncologic treatment
cancer cachexia or cancer anorexia-cachexia syndrome
poor performance status
contraindications to oral nutrition or to high protein nutrition
regular nutritional support at the moment of qualification to the study
patient incompliance at the moment of qualification to the study