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Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease | Clinical Trials | Clareo Health

UNKNOWNNA

Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease

NCT02811653•Centre Hospitalier Universitaire, Amiens

Summary

In AD (Alzheimer disease), the anatomic correlates of attention disorders (as evaluated by motor slowing) have not been thoroughly characterized.

Eligibility

Age

40 - 85 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Patients
•* Age between 40 and 85
•* French mother tongue
•* Consulting at the Amiens Memory Resource and Research Centre (CMRR) for:
•* MCI, according to Albert et al.'s criteria (Albert et al., 2011)
•* Mild dementia (MMSE\>20) due to AD, according to McKhann's criteria (McKhann et al., 2011).
•* Mild dementia due to LBD, according to McKeith et al.'s criteria (McKeith et al., 2005).
•* Mild dementia due to FTLD, according to Rascovsky et al.'s criteria (Rascovsky et al., 2011).
•* Social security coverage
•Healthy controls
+1 more criteria

Exclusion Criteria

•Reading or writing difficulties related to a learning disorder or illiteracy.
•A medical history with a potentially significant impact on cognition (non-corrected thyroid disorders or heart failure):
•* NYHA stage IV dyspnoea.
•* respiratory impairment requiring oxygen therapy.
•* liver impairment.
•* kidney failure, progressing neoplastic disease, or past or present alcohol abuse.
•Past or present neurological disorders other than those having prompted consultation in the Memory Clinic:
•* stroke.
•* meningitis or encephalitis.
•* severe head injury.
+14 more criteria

Locations (1)

CHU Amiens

Amiens, France

Key Dates

Start Date

December 1, 2015

Primary Completion Date

December 1, 2023

Completion Date

December 1, 2023

Last Updated

March 22, 2023

Enrollment

155

ESTIMATED participants

Conditions

Alzheimer Disease

Interventions

Brain MRI

DEVICE

neuropsychological evaluation

OTHER

Blood

BIOLOGICAL

Contacts

Daniela ANDRIUTA, PhD

CONTACT

+33 3 22 66 82 40 andriuta.daniela@chu-amiens.fr

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 22, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease

Inclusion Criteria

Exclusion Criteria

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