Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sheppard Pratt Health System
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Capacity for written informed consent
Age 18-65 years, inclusive
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) diagnosis of schizophrenia or schizoaffective disorder as determined by the Structured Clinical Interview for DSM-5 Disorders (SCID-5)
Currently an outpatient at time of screening
Residual psychotic symptoms of at least moderate severity as evidenced by a Positive and Negative Syndrome Scale (PANSS) total score of 60 or higher AND one or more of the following: one or more PANSS positive symptom scores of 4 or higher; OR containing at least three positive or negative items with scores of 3 or higher at the screening visit
Receiving antipsychotic medication for at least 8 weeks prior to enrolling in the study with no antipsychotic medication changes within the previous 21 days from visit 2 (week 0)
Conformance to PORT Treatment Recommendation about Maintenance Antipsychotic Medication Dose
Proficient in the English language
Participated previously in one of our screening studies
You may not be if
Any clinically significant or unstable medical disorder as determined by the principal investigator and/or the study physician (e.g., HIV infection or other immunodeficiency condition (such as receiving chemotherapy), uncontrolled diabetes, congestive heart failure)
DSM-5 diagnosis of intellectual disability or comparable diagnoses determined by previous versions of the DSM
DSM-5 diagnosis of a moderate or severe substance use disorder, except for caffeine or tobacco, within the last three months prior to the screening visit. If the patient has a positive drug toxicity screen at the time of visit 1 (screening), further evaluation by the investigator will be done of the substance use to determine eligibility.
Any current use of a broccoli supplement (e.g., Avmacol® or other health food broccoli supplement)
Participated in any investigational drug trial in the past 30 days prior to the screening visit
Pregnant, planning to become pregnant, or breastfeeding during the study period
