Enhancing the Public Health Impact of Latent Tuberculosis (TB) Infection Diagnosis and Treatment

Inclusion Criteria

• •Details vary depending on the study tool/measurement being taken. For Phase 1 questionniares (in 4 different populations) criteria are as follows:
• •1. Index case questionnaire:
• •* Newly diagnosed patients with microbiologically confirmed active pulmonary Tuberculosis (Pulmonary Tuberculosis - smear or culture or GeneXpert positive or Nucleic Acid Amplification test (NAAT)
• •* Age ≥ 18 years old
• •* At least 1 Household contact, with contact investigation underway
• •* Signed informed consent
• •* Age ≥ 18 years old
• •* Informed consent signed
• •* Sleeps in the same house at least 1 night per week during the past 3 months with person who has confirmed active Tuberculosis OR
• •* Spent more than one hour per day in the house for at least 5 days per week with person who has active Tuberculosis - in the past 3 months
• •* Health care worker involved in care of Tuberculosis patients, and/or their contacts
• •* Age ≥ 18 years old
• •* Signed informed consent
• •Age ≥ 18 years old
• •Signed informed consent
• •Parent/legal guardian/responsible caregiver of child under 5 years of age
• •And one of the following two mandatory eligibility criteria:
• •Child sleeps in the same house at least 1 night per week during the past 3 months with person who has active pulmonary Tuberculosis OR
• •Child spent more than one hour per day in the house for at least 5 days per week with person who has active pulmonary Tuberculosis ( in the past 3 months)