Loading clinical trials...

Hypertrophic Cardiomyopathy Pilot Study | Clinical Trials | Clareo Health

COMPLETED

Hypertrophic Cardiomyopathy Pilot Study

Pilot Observational Case-control Study of the Electrical Heterogeneity in Patients With Hypertrophic Cardiomyopathy and High Arrhythmic Risk

NCT02806479•Oregon Health and Science University

View on ClinicalTrials.gov

Summary

This study evaluates mechanisms of arrhythmogenicity in hypertrophic cardiomyopathy, in comparison to patients with well-understood arrhythmogenic substrate (ischemic cardiomyopathy), as well as to individuals free from arrhythmogenic substrate

Eligibility

Age

18 - 99 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Diagnosed HCM
•Documented history of sustained ventricular tachyarrhythmia or resuscitated sudden cardiac arrest
•Maximal left ventricular wall thickness of \> 30mm
•Extensive fibrosis on cardiac MRI (\>15% of total myocardial volume)
•\>7.5%/5-year risk of sudden cardiac death as determined by HCM risk-SCD

Exclusion Criteria

•age \< 18 years
•Pregnancy
•Atrial Fibrillation

Locations (1)

Oregon Health and Science University

Portland, Oregon, United States

Key Dates

Start Date

September 1, 2016

Primary Completion Date

September 1, 2020

Completion Date

September 1, 2020

Last Updated

September 16, 2020

Enrollment

ACTUAL participants

Conditions

Hypertrophic CardiomyopathyCoronary Artery Disease

Interventions

Observational: Arrhythmogenic Substrate

OTHER

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

NCT05836259

Hypertrophic Cardiomyopathy

View study

RECRUITING

HCMR Re-Imaging Study

NCT07054073

Hypertrophic Cardiomyopathy (HCM)

View study

RECRUITINGPHASE4

Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI

NCT05681702

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 16, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Hypertrophic Cardiomyopathy Pilot Study

Inclusion Criteria

Exclusion Criteria

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

HCMR Re-Imaging Study

Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI

"Erectile Function After PCI in MI and Non-MI Patients"

Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease

Product Surveillance Registry