Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sanofi
The total study duration will be up to 10 weeks that includes a 6-week treatment period with dose escalation every 2 weeks.
Age
10–17
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female patients aged ≥10 and \<18 years old (at least 4 patients below 16 years old).
Body mass index (BMI) \>85th percentile for age and gender; BMI ≤50 kg/m2.
Male and female patients with documented T2DM insufficiently controlled with metformin at a stable dose and regimen for 8 weeks prior to randomization and/or basal insulin at stable dose (± 20%) and regimen for 8 weeks prior to randomization. The exact individual metformin dose will be selected according to local regulation and to the investigator's medical judgment.
Glycated hemoglobin (HbA1c) \>6.5% and ≤11% at screening.
You may not be if
If female, ongoing pregnancy (defined as positive serum pregnancy test), breast-feeding.
Sexually active postmenarchal female patient who does not agree to use an adequate and highly effective method of contraception throughout the study duration and according to local regulation (ie, hormonal contraception, condom, etc.).
Diabetes other than T2DM.
Fasting plasma glucose \>250 mg/dL (\>13.9 mmol/L) at screening.
Use of other oral or injectable antidiabetic or hypoglycemic agents other than metformin and basal insulin (eg, alpha glucosidase inhibitor, glucagon-like peptide (GLP-1) receptor agonist, dipeptidyl peptidase-IV (DPP-IV) inhibitors, short-acting insulin etc.) within 1 month prior to the screening visit.
History of unexplained pancreatitis, chronic pancreatitis, pancreatectomy, stomach/gastric surgery, inflammatory bowel disease.
The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
