Lead Sponsor

Amgen

Age

55 - 90 years

Sex

FEMALE

Healthy Volunteers

No

•Ambulatory postmenopausal Korean women, ≥ 55 to ≤ 90 years of age at enrollment.
•Postmenopause is defined as no spontaneous vaginal bleeding or spotting for 12 or more consecutive months prior to screening.
•BMD T-score \</= -2.50 at the lumbar spine, total hip or femoral neck.
•At least 2 vertebrae in the L1 through L4 region and at least one hip are evaluable by DXA.

•Subjects with a BMD T-score \</= -4.0 at the lumbar spine, total hip, or femoral neck.
•History of hip fracture.
•Bone disease other than osteoporosis/ or evidence of any other clinically significant disorder, condition/ or disease or significant laboratory abnormalities.
•Known sensitivity or intolerance calcium and vitamin D products.