The subjects volunteer to sign the informed consent
Aged: 18 to 75 years old
Colorectal cancer (AJCC-TNM, high-risk Stage II and Stage III)
The diagnosis and colorectal cancer has been confirmed by pathological examination after radical surgery
The liver and kidney function satisfies the following conditions within 15 days after surgery (excluding day 15): aspartate aminotransferase (AST), glutamic-oxalacetic transaminase (ALT), alkaline phosphatase (ALP)\< 2 upper limit of normal (ULN), total bilirubin ≤ 1.5 ULN, serum creatinine \< 1.5 ULN; normal coagulation function
Other laboratory tests meet the following requirements within 15 days after surgery (excluding day 15): white blood cells count ≥ 3.0×109/L, absolute neutrophil count ≥ 1.5×109/L, platelet count ≥ 100×109/L
ECOG:0-2 points
No other previous history of malignancy.
You may not be if
Multiple primary cancer
Not recover from the colorectal surgery
Presence of organ, bone, or skin metastases
Pregnant or lactating women
Those with active bleeding due to various reasons
Those with HIV infection or AIDS-associated diseases
Those with severe acute and chronic diseases
Those with severe diabetes
Those with serious infectious diseases
Those who can not take drugs by oral route
Drug abusers or those with psychological or mental diseases that may interfere with study compliance
Conditions that are considered not suitable for this study investigators
Clareo Health | Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer