Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Arkansas
Age
40–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 40 to 70.
Cirrhosis, any cause, defined as:
* Biopsy-proven.
* Two or more of the following: albumin \<3.5 g/dL, International Normalized Ration (INR) \>1.3, radiologic or endoscopic evidence of portal hypertension.
Creatinine \<2.0 mg/dL.
Physiologic Model for End Stage Liver Disease (MELD) ≥10.
Decompensated cirrhosis with active or history of variceal bleeding, ascites, hepatic encephalopathy, or jaundice.
Potential transplant candidate as per UAMS criteria
You may not be if
Large gastric or esophageal varices with contraindication to use beta-blockers.
Persistent hepatic encephalopathy grades 2-4.
Prior diagnosis of hepatocellular carcinoma, or hepatic hydrothorax (with prior repeated thoracocentesis).
Cirrhotic cardiomyopathy or congestive heart failure, pulmonary vascular complications, known active coronary artery disease, syncope, and cardiac dysrhythmias.
Physical impediment to perform a cardiorespiratory fitness test.
