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A Randomized, Multicenter, Open-label, Phase 2 Study Evaluating the Efficacy and Safety of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Subjects With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly (>= 65 Years) Acute Myeloid Leukemia (AML) Subjects Not Eligible for Hematopoietic Stem Cell Transplantation (HSCT)
Conditions
Interventions
Azacitidine
Durvalumab
Locations
103
United States
Yale Cancer Center
New Haven, Connecticut, United States
Georgetown University Hospital
Washington D.C., District of Columbia, United States
University of Florida
Gainesville, Florida, United States
Moffitt Cancer Center
Tampa, Florida, United States
University of Chicago
Chicago, Illinois, United States
Hackensack University Medical Center
Hackensack, New Jersey, United States
Start Date
June 3, 2016
Primary Completion Date
December 31, 2018
Completion Date
December 27, 2021
Last Updated
February 28, 2023
NCT06303193
NCT06847867
NCT06465953
NCT06852222
NCT05636514
NCT07270978
Lead Sponsor
Celgene
Data Source & Attribution
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