Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mayo Clinic
With
Patient-Centered Outcomes Research Institute
Age
21–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults, at least 21 years of age
Chronic Migraine - diagnosed according to ICHD3beta criteria
Medication Overuse - diagnosed according to ICHD3beta criteria
Willingness to be randomized to either of the two treatment arms
Willingness to maintain a headache diary
Plan for follow-up care with the clinician
No changes to migraine prophylactic therapy within the 4 weeks prior to randomization.
You may not be if
Younger than 21 years of age
Headache diagnoses other than chronic migraine with medication overuse; episodic tension-type headache on 3 or fewer days per month is allowed
Not willing to be randomized to either of the treatment arms
Not willing to maintain a daily headache diary
Not planning on follow-up care with the clinician
In the opinion of the clinician, randomization to either treatment arm would be considered unsafe (ex: pregnancy, immediate discontinuation
Prisoners
Diminished decision-making capacity which in the investigator's opinion would interfere with the person's ability to provide informed consent and complete study procedures.
