National Institute of Neurological Disorders and Stroke (NINDS)
National Institute on Aging (NIA)
The purpose of this study is to use a brain imaging method called PIB PET and VAT PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia. The investigators will be including both PD and normal subjects in this study. This a long term study and we are considering including a total of 320 participants in this protocol.
Age
50–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
PD patients must exhibit three of the following cardinal signs: rest tremor, rigidity, bradykinesia, or postural instability; or two of these features with one of the first three displaying asymmetry.
You may not be if
history of head trauma, major neurological or psychiatric diseases other than Parkinson disease and dementia, e.g. stroke, multiple sclerosis, depression or schizophrenia.
severe systemic diseases.
inability to lie still for 90 minutes.
metallic implants, pacemakers, or any other contraindication to MRI.
refusal to consent to brain donation.
Clareo Health | Investigations of Dementia in Parkinson Disease
