Chemotherapy before

Stem cell transplantation before

History of malignancy, except for basal cell or squamous cell carcinoma of the skin or carcinoma in situ of the cervix

Uncontrollable cardio-cerebral vascular, coagulative, autoimmune, serious infectious disease

Primary cutaneous, CNS DLBCL

LVEF≤50%

Other uncontrollable medical condition that may that may interfere the participation of the study

Lab at enrollment(unless caused by lymphoma) Neutrophile\<1.5\*10\^9/L Platelet\<80\*10\^9/L Hemoglobulin\<100g/L ALT or AST \>2\*ULN,AKP or bilirubin \>1.5\*ULN Creatinine\>1.5\*ULN

Not able to comply to the protocol for mental or other unknown reasons

Pregnant or lactation

If HbsAg positive, should check HBV DNA, DNA positive patients cannot be enrolled. If HBsAg negative but HBcAb positive (whatever HBsAb status), should check HBV DNA,DNA positive patients cannot be enrolled.

HIV infection

Reduced Chemotherapy in Low Risk DLBCL

What this study is about