Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Memorial Sloan Kettering Cancer Center
With
Washington University School of Medicine
The Cleveland Clinic
Vanderbilt University School of Medicine
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients ≥18 years old scheduled for elective thoracic surgery (segmentectomy, lobectomy or bi-lobectomy, pneumonectomy or esophagectomy) and meeting one of the four following risk criteria:
* 1\. Female \& BNP ≥ 25pg/ml (no age limit)
* 2\. Male gender \<75 \& BNP ≥ 25pg/ml
* 3\. Male- age ≥75 (No BNP limit)
* 4\. History of prior AF
Patients in sinus rhythm.
Patients with stable respiratory status (no respiratory distress).
Patients capable of providing written, informed consent.
You may not be if
Patients scheduled for extrapleural pneumonectomy.
Hemodynamically unstable patients (not in cardiogenic shock or having an acute MI).
Patients with 2nd or 3rd degree atrioventricular (AV) block.
Patients with hypersensitivity to amiodarone or NAC.
Patients already taking class Ic or III antiarrhythmic drugs.
Hepatic insufficiency (≤2 times the upper normal limit of transaminase levels).
Renal insufficiency (creatinine ≥2.0 mg/dl).
Known pregnancy.
Clareo Health | Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery