Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Prem Soman
With
Astellas Pharma US, Inc.
Patients who are previously scheduled for diagnostic coronary angiography will be approached for consent to be part of the study. If the patient is found to have one or two vessel disease and it is planned by the interventional cardiologist that FFR will be used, then the previously consented patient will be deemed appropriate for the study. The standard procedure will be followed for FFR testing using regadenoson. The patient will then receive the standard dose of Tc-99m sestamibi. The interventional cardiologist will proceed with percutaneous coronary intervention (PCI) if appropriate. Patients will proceed to the cardiac catheterization laboratory holding area post procedure. Patients will then be scheduled to be taken to the nuclear cardiology laboratory one to three hours following the coronary angiogram for standard SPECT acquisition. Patients will be monitored for 2-6 hours or overnight as clinically indicated following diagnostic coronary angiography and PCI. Low dose resting myocardial perfusion scanning may be performed the next day if stress myocardial perfusion study was abnormal.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients undergoing clinically-indicated FFR measurement (to determine the hemodynamic significance of intermediate degrees of stenosis) for single or two -vessel epicardial coronary disease during diagnostic coronary angiography for suspected coronary artery disease.
You may not be if
1. Patients with 3-vessel disease
2. Prior coronary artery bypass grafting
3. Patients with second or third- degree atrioventricular block, without a functioning pacemaker
4. Patients who have ingested caffeine-containing products within the past 12 hours.
Clareo Health | Simultaneous Assessment of FFR and SPECT
