Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Stanford University
Age
8–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Voluntarily sign written informed consent.
Male or non-pregnant and non-lactating females at least 8 years of age.
Confirmed diagnosis of active, mild to moderate ulcerative proctitis or proctosigmoiditis extending no further than 40cm from the anal verge. Typically, baseline Mayo Disease Activity Index (MMDAI) score between 5 and 10 (indicating mild to moderate disease).
You may not be if
Known infection with Clostridium difficile (C. difficile) and/or other enteric pathogens
5-aminosalicylic acid (5-ASA) intolerance
Current or recent (3 weeks) oral or rectal steroids
History of thiopurine or Anti-tumor necrosis factor (Anti-TNF) alpha treatment for colitis
Abnormal creatinine
Previous small bowel or colonic resection,
Anal sphincter incompetence,
Current smokers.
History or current diagnosis of Crohn's disease or indeterminate colitis.
History of diverticulitis, collagenous colitis, celiac disease, recurrent pancreatic or known gallbladder disease.
Unstable significant cardiovascular, endocrine, neurologic or pulmonary disease.
Hemoglobin levels \< 7.5 g/dL.
History of sclerosing cholangitis, cirrhosis, or hepatic impairment
Pregnant or at risk of pregnancy.
Some medications to treat UC are prohibited during participation in the study, including laxatives and anti-diarrhea medications; oral 5-ASA agents and daily fiber supplements are allowed.
