Clinical Trial of CBS-2004 in Prevention of Travelers' Diarrhea

Exclusion Criteria

• •1. Allergy to investigational product
• •2. History of functional bowel disorder (including IBS)
• •3. Chronic intestinal disease (ulcerative colitis, crohn's disease), post vagotomy diabetic autonomic neuropathy, malabsorption, short bowel syndrome, celiac disease, bacterial overgrowth due to blind loops, pancreatitis
• •4. Antibiotic use within 7 days prior to enrollment (except for malaria prophylaxis excluding doxycycline)
• •5. Use of other probiotics or prebiotics (outside of the study product) in the prior 3-weeks or intent to use during the study period. This includes the over-the-counter preparations of probiotics, prebiotics (including inulin, lactulose) or consumption of a bio-yogurt product.
• •6. Lactose intolerant (allergies to dairy products).
• •7. Medications usage as deemed by the PI to interfere with GI function
• •8. Diarrheal illness within 7 days prior to enrollment
• •9. Subject has a concomitant disease or condition that could interfere with or for which treatment could interfere with the conduct of the study, or could in the opinion of the investigator increase the risk of adverse events (AEs) during the subject's participation in the study.
• •10. Use of any investigational or non-registered drug other than the study drug within 30 days preceding the study enrollment.