Finding studies
Finding studies
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Lead
Xinqiao Hospital of Chongqing
With
Primary Objectives 1. To determine the safety of CD22.CAR-T cells in lymphoma patients refractory or resistent to anti-CD19:TCRz:CD28 CAR-T cells 2. To determine in vivo dynamics and persistency of CD22.CAR-T cells. Secondary Objectives 1. To determine the feasibility of CD22.CAR-T cells in lymphoma patients refractory or resistent to anti-CD19:TCRz:CD28 CAR-T cells 2. To determine in vivo dynamics and persistency of CD22.CAR-T cells. 3. To assess the intratumoral infiltration of CD22.CAR-T cells. 4. To correlate the subsets and differentiation of CD22.CAR-T cells to observed anti-tumor efficacy
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted