Lead Sponsor

Alkermes, Inc.

Age

18 - 55 years

Sex

ALL

Healthy Volunteers

No

•Subject has a body mass index (BMI) of 18.0-30.0 kg/m\^2, inclusive, at Visit 1 and Visit 2
•Subject meets the DSM-5 criteria for a primary diagnosis of schizophrenia
•Subject is appropriate for outpatient treatment; has no hospitalizations for acute exacerbations of schizophrenia within 6 months before Visit 1
•Subject has maintained a stable body weight (change \</= 5%) for at least 3 months prior to Visit 1 based on self-report
•Additional criteria may apply

•Subject has any of the following psychiatric conditions per DSM-5 criteria:
•Diagnosis of schizoaffective disorder or bipolar I or II disorder, or current, untreated or unstable major depressive disorder
•Clinically significant cognitive difficulties present within the past 2 years that could interfere with participation in the study
•Drug-induced or toxic psychosis
•Any other psychiatric condition that could interfere with participation in the study
•Subject poses a current suicide risk at Visit 1 or Visit 2 in the opinion of the investigator
•Subject has inflammatory bowel disease or any other gastrointestinal disorder associated with weight loss, anorexia nervosa, or binge eating disorder
•Additional criteria may apply