A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Exclusion Criteria

• •1. Patients who are pregnant, planning to become pregnant in the next 12 months, or lactating.
• •2. CHF hospitalization within the last 1 month prior to enrollment.\*
• •3. Acute coronary syndrome in the last 1 month prior to enrollment.\*
• •4. HIV positive, or active, untreated HCV as determined by review of medical records.
• •5. History of cancer within the last 5 years, except basal cell skin carcinoma
• •6. Inability to provide written informed consent due to cognitive or language barriers (interpreter permitted).
• •7. Concurrent enrollment in another clinical investigative trial that may alter the outcomes of enrollment in this trial.
• •8. Any condition requiring immunosuppressant medications (e.g., for treatment of organ transplants, psoriasis, Crohn's disease, alopecia areata).
• •9. Presence of any clinical condition that in the opinion of the PI or the sponsor makes the patient not suitable to participate in the trial.
• •* As defined by the standard definitions of CHF and ACS by the American Heart Association.