PRIMARY OBJECTIVES:
I. To assess the feasibility of utilizing an MRI-guided tri-60Co teletherapy system for liver SBRT, as determined the treating radiation oncologist's ability to accurately visualize and align to the target lesion(s).
II. To assess the feasibility of using a three versus five fraction scheme, for one versus multiple (i.e., =\< 5) target lesions.
SECONDARY OBJECTIVES:
I. To determine the tumor local control (LC), disease specific survival (DSS), and overall survival (OS).
II. To gather biomarkers that may elucidate differential immunogenic responses from the three versus the five fraction SBRT regimens.
OUTLINE:
Patients undergo MRI-guided Tri-60Co teletherapy SBRT 3-5 fractions over 1-2 weeks.
After completion of study treatment, patients are followed up at approximately 4-6 weeks, and then every 3 months for 2 years.
