Have known allergies to abemaciclib, related compounds, or any components of the formulation

Regularly use known drugs of abuse and/or show positive findings on urinary drug screening

Show evidence of human immunodeficiency virus (HIV) infection and/or positive human HIV antibodies

Show evidence of hepatitis C and/or positive hepatitis C antibody

Show evidence of hepatitis B and/or positive hepatitis B surface antigen

A Study of Abemaciclib in Healthy Participants