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A Study of Durvalumab (MEDI4736) and Monalizumab in Solid Tumors | Clinical Trials | Clareo Health

Active Not RecruitingPhase 1/2NCT02671435

A Study of Durvalumab (MEDI4736) and Monalizumab in Solid Tumors

This is a multicenter, open-label, dose-escalation, dose-exploration and dose-expansion study to evaluate the safety, tolerability, antitumor activity, pharmacokinetic (PK), pharmacodynamics, and immu...

Lead sponsor: MedImmune LLC•22 U.S. locations•View source on ClinicalTrials.gov

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 15, 2026Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhasePHASE1/PHASE2

Enrollment383

Start dateFeb 2016

Last updatedJun 15, 2026

Condition

Advanced Solid Tumors

Locations shown

Research Site

Birmingham, Alabama

Research Site

Scottsdale, Arizona

Research Site

Duarte, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 15, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Study of Durvalumab (MEDI4736) and Monalizumab in Solid Tumors

What this study is about

Save this trial guide to your notes

Sponsors

Related studies

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

A Study of Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

A Study of PHST001 in Advanced Solid Tumors

Study of CM518D1 in Patients With Advanced Solid Tumors

Trial snapshot

Condition

Locations shown

For caregivers