A Study of A-101 Solution in Subjects With Common Warts.

Exclusion Criteria

• •1. Subject has clinically atypical warts on the trunk or extremities
• •2. Subject is immune compromised (due to chemotherapy, systemic steroids, genetic immunodeficiency, transplant status, etc.)
• •3. Subject has a history of Human Immunodeficiency Virus (HIV) infection
• •4. Subject has had any Human Papilloma Virus (HPV) vaccine within 1 year prior to enrollment
• •5. Subject has used any of the following intralesional therapies within the specified period prior to enrollment to the Target Wart:
• •* Immunotherapy (Candida antigen, mumps antigen, Trichophyton antigen);
• •* Anti-metabolite therapy (bleomycin, 5-fluorouracil)
• •6. Subject has used any of the following systemic therapies within the specified period prior to enrollment:
• •* Immunomodulatory/immunosuppressant therapy (e.g., etanercept, alefacept, infliximab);
• •* Glucocortico-steroids (inhaled and intra-nasal steroids are permitted);
• •7. Subject has used any of the following topical therapies within the specified period prior to enrollment on, or in a proximity to the Target Wart, which in the Investigator's opinion, might put the subject at undue risk by study participation or interfere with the study conduct or evaluations:
• •\- LASER (pulsed-dye laser), light (intense pulsed light, photo-dynamic therapy, other energy based therapy); Immuno-therapy ( imiquimod, squaric acid dibutyl ester, etc.); Anti-metabolite therapy (5-fluorouracil); Retinoids; Liquid nitrogen, electrodesiccation, curettage; Over-the-counter wart therapies
• •8. Subject has had any of the following within the specified period prior to enrollment on, or in a proximity to the target lesion, which in the Investigator's opinion, might put the subject at undue risk by study participation or interfere with the study conduct or evaluations:
• •* A cutaneous malignancy;
• •* A pre-malignancy (actinic keratosis)
• •9. Subject has a history of sensitivity to any of the ingredients in the study medications
• •10. Subject has any current skin disease (psoriasis, atopic dermatitis, eczema, sun damage, etc.), skin condition (sunburn, open wounds) or other disease or condition (uncontrolled diabetes) which, in the Investigator's opinion, might put the subject at undue risk by study participation or interfere with the study conduct or evaluations
• •11. Subject has participated in an investigational drug trial in which administration of an investigational study medication occurred within 30 days prior to enrollment.