Study of DS-5141b in Patients With Duchenne Muscular Dystrophy

Inclusion Criteria

• •Confirmation of out-of-frame deletion(s) that could be corrected by dystrophin gene exon 45 skipping.
• •Intact muscles of adequate quality for biopsy to allow evaluation of the efficacy of the study drug.
• •Boys aged from 5 years to \<11 years.
• •Patients able to walk at least 325 meters in the 6-minutes walk test.
• •Glucocorticoid-naive patients, or patients who have used glucocorticoids for at least 6 months prior to enrollment in this study with no dose changes for at least 3 months prior to enrollment.