Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial Hemosiderosis

Exclusion Criteria

• •The patient is participating in another interventional study
• •The patient is in an exclusion period determined by a previous study
• •The patient is under judicial protection
• •The subject (next of kin or legal representative) refuses to sign the consent
• •It is not possible to give the subject or his/her representative informed information
• •The patient has an contra-indication for performing an MRI
• •The patient is in the acute phase (the tracer does not bind in cases of large hematoma)
• •The patient is participating in another interventional study
• •The patient is in an exclusion period determined by a previous study
• •The patient is under judicial protection
• •The subject (next of kin or legal representative) refuses to sign the consent
• •It is not possible to give the subject or his/her representative informed information
• •The patient has an contra-indication for performing an MRI
• •The patient is in the acute phase (the tracer does not bind in cases of large hematoma)
• •The patient is participating in another interventional study
• •The patient is in an exclusion period determined by a previous study
• •The patient is under judicial protection
• •The subject (next of kin or legal representative) refuses to sign the consent
• •It is not possible to give the subject or his/her representative informed information
• •The patient has an contra-indication for performing an MRI
• •The patient is in the acute phase (the tracer does not bind in cases of large hematoma)
• •Haemosiderosis or history of lobar hematoma or other visible cerebral history on MRI
• •The subject is participating in another interventional study
• •The subject is in an exclusion period determined by a previous study
• •The subject is under judicial protection
• •The subject (next of kin or legal representative) refuses to sign the consent
• •It is not possible to give the subject or his/her representative informed information
• •The subject has an contra-indication for performing an MRI
• •Abnormal MRI
• •The groups will be matched according to sex and age (by increments of 5 years) to the extent possible. Because amyloid cerebral angiopathy is a very rare condition, matching the two factors may be difficult to achieve. We therefore anticipate where appropriate to focus matching on age.