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Timolol Eye Drops in the Treatment of Acute Migraine Headache | Clinical Trials | Clareo Health

TERMINATEDNA

Timolol Eye Drops in the Treatment of Acute Migraine Headache

NCT02630719•University of Missouri, Kansas City

Summary

The goal of this study is to determine whether timolol eye drops are effective in alleviating acute migraine headaches. Subjects will be randomized to receive either timolol eye drops or placebo (tears) to use as a migraine abortive medication.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Diagnosis of migraine headache

Exclusion Criteria

•Non-migraine headache
•Use of systemic beta-blocker
•Medical history of hypotension, bradycardia, syncope or other significant cardiovascular disease
•Medical history of difficulty breathing, asthma or chronic obstructive pulmonary disease or other pulmonary disease
•Medical history of glaucoma, ocular hypertension or hypotony, punctual stenosis, current use of other ophthalmic medications
•Previous adverse reaction to timolol or other beta-blockers
•Inability to self-administer eye drop due to physical or cognitive disorders
•Currently pregnant or breastfeeding
•Pregnant in the past year
•Non-english speaker

Locations (1)

Truman Medical Center

Kansas City, Missouri, United States

Key Dates

Start Date

January 1, 2016

Primary Completion Date

August 1, 2017

Completion Date

August 1, 2017

Last Updated

May 15, 2019

Enrollment

ACTUAL participants

Conditions

Migraine

Interventions

Timolol eye drops

DRUG

Artificial tears

DRUG

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 15, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Timolol Eye Drops in the Treatment of Acute Migraine Headache

Inclusion Criteria

Exclusion Criteria

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Mind Body Balance for Pediatric Migraine

Light Exposure, Migraine Outcomes, and Sleep Quality

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Prophylactic Treatment With Atorvastatin for Episodic Migraine.