A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

Inclusion Criteria

• •Participant either must have ceased lactating at Screening; or if still lactating at Screening, must have already fully and permanently weaned their infant(s) from breastmilk; or if still actively breastfeeding at Screening, must agree to cease giving breastmilk to their infant(s) prior to receiving study drug.
• •Participant had a major depressive episode that began no earlier than the third trimester and no later than the first 4 weeks following delivery, as diagnosed by Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I).
• •Participant was less than or equal to (\<=) six months postpartum.
• •Participant must be amenable to intravenous therapy.