Acute Effects of Gabapentin in Sleep Parameters and Hormonal Release During Sleep in Older Men

Exclusion Criteria

• •Basal Apnea-Hypopnea index (aHI)\>=15
• •Restless Legs Syndrome Symptons
• •BMI less than 18.5 kg/m2 or greater than 30 kg/m2
• •Less than 30 min. of regular physical activity (at least walking inside home, etc.)
• •Plasma albumin below 3.5 mg/dL
• •Psychoactive drugs use
• •Drugs with muscle anabolic potential
• •Current treatment for obesity or weight gain
• •Enteral or parenteral feeding
• •Inability to walk without assistance,
• •Loss of independence in any activity of daily living
• •Nocturia above 2 episodes
• •Smoking more than 2 cigarettes per day
• •Alcoholism (more than 2 doses a day)
• •Prior epilepsy diagnosis
• •Clinically evident atherosclerotic disease
• •Dementia
• •Depression
• •Rheumatic diseases
• •Cancer
• •Diabetes (poorly controlled, HbA1C \> 7,0, requirement of insulin)
• •Thyroid dysfunction without treatment
• •Advanced stages in COPD, HF, liver or renal failure