An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.
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Keep this study
Lead
Bristol-Myers Squibb
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com
For Dose Escalation:
* Subjects with any previously treated advanced (metastatic or refractory) solid tumor
For Cohort Expansion:
* Subjects must have a previously treated advanced solid tumor to be eligible
Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Willing and able to provide pre-treatment and on-treatment fresh tumor biopsy
Women of child-bearing potential and men must use an acceptable method of contraception during treatment and for 23 weeks after treatment for women and 31 weeks for men
You may not be if
Known central nervous system metastases or central nervous system as the only source of disease
Other concomitant malignancies (with some exceptions per protocol)
Active, known or suspected autoimmune disease
Uncontrolled or significant cardiovascular disease
History of active or chronic hepatitis (e.g. Hep B or C)
Impaired liver or bone marrow function
Major surgery less than 1 month before start of the study
Clareo Health | An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.
