Ovarian adenocarcinoma stage IIIa, IIIb or IV pleural, cytologically or histologically proven

Patient scheduled to undergo neoadjuvant chemotherapy based on platinum followed by surgery and adjuvant chemotherapy

Age ≥ 18 years .

Performance status ECOG \> or = 2

Adequate haemoglobin rate ≥ 10 g/dL

Ability to provide written informed consent

Patient's legal capacity to consent to study participation

HE4 as a Relapse Biomarker in Ovarian Cancers