able to speak/read English

diagnosed with chronic phase CML

not have been treated for other cancer (except non-melanoma skin cancer) in the past 5 years

be under the care of a Moffitt Cancer Center (MCC) physician

be on a stable dose of the same oral TKI for \>= 3 months

new onset or worsening of fatigue since starting TKI

report moderate-severe fatigue in past week (FSI average rating \>= 4 of 0-10)

have no clinical history of disease (e.g., multiple sclerosis, fibromyalgia) that could account for their fatigue presentation

Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention