Finding studies
Finding studies
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Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
Medicines for Malaria Venture
With
Cohort 1: * Controlled human malaria infection on Day 0 (Direct Venous Inoculation of 3200 cryopreserved Plasmodium falciparum sporozoites) * Drug administration on Day -3 * 8 subjects: 6 DSM265 400 mg: 2 matching placebo Clinical safety review of Cohort 1 in order to proceed to Cohorts 2a and 2b Cohort 2a: * Controlled human malaria infection on Day 0 (Direct Venous Inoculation of 3200 cryopreserved Plasmodium falciparum sporozoites) * Drug administration on Day -X (to be defined following safety and pharmacokinetic data) * 8 subjects: 6 DSM265 400 mg: 2 matching placebo Cohort 2b: * Controlled human malaria infection on Day 0 (infected mosquito bite) * Drug administration on Day -X (to be defined following safety and pharmacokinetic data) * 8 subjects: 6 DSM265 400 mg: 2 matching placebo
Age
18–45
Sex
ALL
Healthy volunteers
Accepted