A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus

Exclusion Criteria

• •Subjects with known BE.
• •* Patients with prior history of ablation (photodynamic therapy, radiofrequency ablation, cryotherapy, argon plasma coagulation). Patients with history of endoscopic mucosal resection alone will not be excluded.
• •* Patients with history of esophageal resection for esophageal carcinoma. Subjects with or without known evidence of BE (on history or review of medical records).
• •* Pregnant or lactating females.
• •* Patients who are unable to consent.
• •* Patients with current history of eosinophilic esophagitis, achalasia or uninvestigated dysphagia.
• •* Patients on oral anticoagulation including Coumadin, Warfarin.
• •* Patients on antiplatelet agents including Clopidogrel, unless discontinued for 3 days prior to the sponge procedure.
• •* Patients on oral thrombin inhibitors including Dabigatran and oral factor X a inhibitors such as rivaroxaban, apixaban and edoxaban, unless discontinued for 3 days prior to the sponge procedure.
• •* Patients with history of known varices or cirrhosis.
• •* Patients with history of esophageal resection for esophageal carcinoma.
• •* Patients with congenital or acquired bleeding diatheses.
• •* Patients with a history of esophageal squamous dysplasia.
• •* Patient has known carcinoma of the foregut (pancreatic, bile duct, ampullary, stomach, or duodenum) within 5 years prior to study enrollment.