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How to Test Success of a Renal Denervation | Clinical Trials | Clareo Health

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TERMINATEDNCT02559882

How to Test Success of a Renal Denervation

The study aimed to assess the success of a clinically indicated renal denervation by different tests and correlate the results of the tests with the clinical outcome.

Lead sponsor: University of Zurich•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Zurich

We aim to test the response to adenosine infusion, cold pressure test, flow mediated dilation of renal artery before and after a clinical indicated renal denervation. Renal Denervation is not a study intervention

Age

18 - 85 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Male and female patients 18 years to 85 years of age, with a diagnosis of re-sistant hypertension (office sitting blood pressure \>140/90 mmHg and 24-hour blood pressure \>130/80 mmHg in patients treated with at least three antihypertensive drugs including a diuretic) and a clinical indication for a renal denervation.

Exclusion Criteria

•Secondary cause of hypertension
•Anatomical contraindication to renal denervation (renal artery diameter less than 4 mm or more than 8 mm), multiple renal artery, length to bifurcation less than 2 cm
•Heart failure (normal ejection fractions on echocardiography and no clinical signs and symptoms of heart failure).
•Alcohol or drug abuse,
•Malignancy (unless healed or remission \> 5 years)
•Pregnancy
•Know allergy to contrast medium
•Participation in another study within the last month

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 14, 2019Terms

Trial snapshot

StatusTERMINATED

Phase—

Enrollment11

Start dateAug 2015

Last updatedJan 14, 2019

Condition

Hypertension, Resistant to Conventional Therapy

Locations shown

Department of Cardiology University Heart Center Zurich University Hospital

Zurich

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 14, 2019Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions