A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes

Exclusion Criteria

• •Anti-diabetic drugs (oral or subcutaneous) in the last 2 months.
• •Lipid-lowering drugs in the last 2 months.
• •Gouty arthritis in the last 2 years or uric acid \> 735 mg/dl.
• •Presence of uncontrolled endocrinological pathology (including hypothyroidism).
• •Hepatic chronic disease (glomerular filtration rate \< 45 ml/min).
• •Renal, inflammatory or tumoral diseases.
• •Drugs which could interfere in glucose or lipid metabolism such as androgens, corticosteroids (except for those with topic administration) and estrogen replacement therapy.
• •Intake of functional foods with plant sterols in the past 6 weeks.
• •High alcohol intake (\> 30 g per day).
• •Any serious disease which involves less than 1 year life expectancy or, in investigators judgment, limit the follow-up of an homogeneous diet throughout the study.
• •Pregnancy or intention of pregnancy during the study.