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Breast reconstruction is an integral part of the management of patients with breast cancer and treated by total mastectomy. The aim of breast reconstruction is to get a satisfying aesthetic and functional result (sensitivity) and that would enable the patient to appropriate the reconstructed breast. Patient satisfaction assessed subjectively by questionnaires would be better in autologous reconstructions than in reconstructions by prosthesis. The aim of our trial is to use functional MRI (fMRI) as an objective evaluation tool to describe the brain functional changes of sensory projections after immediate or secondary breast reconstruction.
Patients responding criteria for selection and not objecting to participate in this trial will address a quality of life questionnaire at baseline. Then the study procedures differ depending on which group the patient belongs to. Immediate breast reconstruction group : Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form. Secondary breast reconstruction group : * In the two months preceding the surgery, a preoperative fMRI will be performed. * Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form.
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
No
Centre Oscar Lambret
Lille, France
Start Date
January 7, 2016
Primary Completion Date
November 25, 2019
Completion Date
April 15, 2021
Last Updated
March 17, 2026
49
ACTUAL participants
Functional MRI
DEVICE
Lead Sponsor
Centre Oscar Lambret
Collaborators
NCT04550494
NCT04704661
Data Source & Attribution
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