Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Icahn School of Medicine at Mount Sinai
With
Columbia University
New York Stem Cell Foundation Research Institute
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
male and female subjects age 18 or older
diagnosis of one of the following:
1. RRMS according to McDonald 2010 criteria or a diagnosis of CIS with clinical symptoms and MRI consistent with MS
2. PPMS according to McDonald 2010 criteria
3. SPMS defined as at least six months of progressive decline following an initial relapsing disease course
able and willing to undergo clinical evaluation, MRI, lumbar puncture, and skin biopsy and to return for follow up assessments at the end of year 1 and year 2
able and willing to provide informed consent.
You may not be if
pregnancy
inability to undergo lumbar puncture, due to anticoagulant therapy that cannot be held for the day of the procedure or results of screening laboratory testing or the presence of another medical condition that would render the procedure unsafe, as determined by the investigator
inability to undergo MRI, due to the presence of metallic implants incompatible with MRI or any other reason
presence of other severe medical conditions likely to influence study results or that raise the likelihood of harm to the patient as a result of study participation, as determined by the investigator (e.g. the presence of a brain mass, which could influence the CSF results and also might make lumbar puncture unsafe)
