Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Tennessee Graduate School of Medicine
Design: Open-label, single-center prospective study. Setting: Trauma/Surgical Intensive Care Unit (TSICU) at a Level I academic trauma center.
Patients: Patients 18 years of age or older requiring mechanical ventilation and admitted to the TSICU Interventions: Patients were randomly assigned based on unit bed location to receive dexmedetomidine or propofol for sedation.
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Patients were included in the study if they were 18 years of age or older,
mechanically ventilated,
placed on the institutional sedation protocol,
expected to require sedation lasting 24 hours after randomization, and
admitted to the TSICU and followed by the Trauma/Surgical Service.
You may not be if
Patients were excluded for any of the following:
72 hours or greater since sedation protocol initiation,
treatment per the institutional traumatic brain injury (TBI) protocol,
concomitant continuous infusion of a neuromuscular blocking agent,
heart rate less than 50 beats per minute,
mean arterial pressure less than 55 mmHg despite fluid resuscitation and vasopressors, and
use of other alpha-2 agonists within 24 hours of randomization.
