Intra Oral Kinetics of Fluoride Containing Dentifrices

Exclusion Criteria

• •Pregnant or breast feeding women
• •Presence of chronic debilitating disease.
• •Any condition that causes xerostomia as determined by the Investigator.
• •Evidence of untreated caries.
• •Gross periodontal disease.
• •Tongue or lip piercing or presence of dental implants. Professional tooth cleaning or dental treatment during study. Oral surgery or extraction within 6 weeks of the screening visit.
• •Self reported oral symptoms including lesions, sores or inflammation
• •Known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients
• •Currently taking antibiotics or have taken antibiotics within 2 weeks of the screening visit
• •Any medication that could affect salivary flow or cause xerostomia as determined by the Investigator
• •Use of multivitamins, calcium supplements and or fluoride supplements within 7 days of treatment phase
• •Participant unwilling to abstain from smoking for at least 4 hours on the day of each test visit
• •Recent history (within the last year) of alcohol or other substance abuse.