A Confirmatory Study for Evaluation of the Treatment by the Celluma3 of Periorbital Wrinkles

Exclusion Criteria

• •1. Subject who is pregnant, nursing, or planning to become pregnant during the course of the study.
• •2. Subjects who have any history of diabetes.
• •3. Subjects who, in the preceding 12 months prior to the study start, have:
• •1. Been exposed to hyaluronic acid, or
• •2. any other filler, or
• •3. injection for cosmetic purposes related to the face, or
• •4. undergone any cosmetic procedure for the face, or
• •5. had an active cut, wound or infection of the face, or
• •6. had oral isotretinon.
• •4. Subjects who, in the preceding six months prior to the study start, have:
• •1. Had any botulinum toxin ("Botox"), or
• •2. had ablative skin resurfacing on the glabellar area.
• •5. Subjects who, in the preceding three months prior to the study start, have:
• •1. Had retinoid, microdermabrasion or prescription level glycolic acid treatments, or
• •2. had any compromising procedure in the opinion of any clinical evaluator.
• •6. Any other diagnosis of any contraindication in the current User Manual.