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Keep this study
Lead
University of Florida
With
American Brain Foundation
Neuronetics
rTMS refers to the application of transcranial magnetic stimulation (TMS) pulses to a specific target at predefined stimulation parameters. Repeated sessions of rTMS therapy have been demonstrated to induce cumulative persistent benefits that can last weeks after the conclusion of the rTMS sessions
The central hypothesis of this study is that rTMS therapy in PCD can potentiate the effects of BoNT injections. With the current standard treatment, the peak-dose benefits seen with BoNT are seen at about 4-6 weeks after the administration of injections. The investigator will introduce a 1 week course of rTMS around 2-8 weeks before or after BoNT or T1). The investigator will examine the effects of combined therapy at 10 weeks after BoNT and 12 weeks after BoNT injections follow-up.
Age
30–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of PCD in accordance with the Consensus Statement of the Movement Disorder Society
Subjects who report Botulinum Toxin benefits lasting 10 weeks or less only (suboptimal benefits with standard care)
You may not be if
Pregnancy
Active seizure disorder
Presence of a metallic body such as pacemaker, implants, metal rods and hearing aid.
Clareo Health | rTMS and Botulinum Toxin in Primary Cervical Dystonia
