Fish Oil Brain Delivery Study

Exclusion Criteria

• •1. Current smokers (or a recent history of smoking within less than 5 years),
• •2. Having a history of cardiovascular disease defined by a prior heart attack, coronary bypass or percutaneous luminal angioplasty, kidney failure or blindness.
• •3. a diagnosis of cancer in the past 6 months, uncontrolled hyper- or hypothyroidism
• •4. Taking anti-coagulants such as warfarin
• •5. Anyone consuming n-3 PUFA capsules for the last 3 months.
• •6. regular exercisers (\>5 X30min of aerobic exercise per week),
• •7. heavy drinkers (\>30 units of alcohol per week). One unit of alcohol is about equal to: half a pint of ordinary strength beer, lager or cider (3-4% alcohol by volume); or. a small pub measure (25 ml) of spirits (40% alcohol by volume); or. a standard pub measure (50 ml) of fortified wine such as sherry or port (20% alcohol by volume)
• •8. If participants have scores that lie 2 SD outside the means of the neuropsychiatry tests administered, they will have mild cognitive impairment. Participant's with mild cognitive impairment are excluded from this study.