The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy

Exclusion Criteria

• •1. Patients hypersensitive to bovine protein
• •2. Patients hypersensitive to gentamicin antibiotics
• •3. Patients with inflammatory arthritis such as rheumatoid arthritis, gout arthritis
• •4. Patients with arthritis related to autoimmune disease
• •5. Pregnant, breast-feeding patients or those who have a possibility of pregnancy
• •6. Patients with accompanying diseases other than articular cartilage defects, including tumors (Exception: if the possibility of Chondron treatment is confirmed with doctor's clinical decision).
• •7. Patients who have a history of receiving radiotherapy, chemotherapy in the last 2 years (Exception: if the possibility of Chondron treatment is confirmed with doctor's clinical decision).
• •8. Patients with diabetes (however, patients whose blood sugar test results are normal and do not have any complication of diabetes, when a written opinion that CHONDRON administration is possible is appended by a doctor are excluded)
• •9. Patients with an infection that required hospitalization for antibiotics or the administration of antiseptic agents
• •10. Patients under adrenocorticoid therapy (Exception: if the possibility of Chondron treatment is confirmed with doctor's clinical decision).
• •11. Patients with psychiatric disorder and those who are considered to be inappropriate for this trial by the judgment of the clinical trial manager
• •12. Patients with cartilage defects in both knees (If the necessity of other surgery on the opposite side of knee joint using Chondron is confirmed with doctor's clinical decision).
• •13. Patients with liver, heart, or kidney disease (Those who show normal or insignificant test results may be enrolled in this study and receive the Chondron based on the investigator's judgment. Hypertension patients are allowed.)
• •14. Patients who had been infected with a virus (Those who show normal or insignificant test results may be enrolled in this study and receive the Chondron based on the investigator's judgment.)
• •15. Patients who had participated in another clinical trial (limited to those who participated in other studies on fracture within the last six months.)